Normalizes the ChIP-seq read counts by scaling to the reference ChIP-seq library size, and transforms the ChIP-seq read counts.
normalize_chip(
chip_counts,
idxstats_file,
ref_size = 2e+07,
transform = c("none", "asinh", "log2", "sqrt")
)
A vector of ChIP-seq counts.
The idxstats
file generated by samtools
.
ChIP-Seq reference library size (Default: 20 million).
Type of transformation for the ChIP read counts. Options are ‘none’ (no transformation), ‘asinh’, ‘log2’, and ‘'sqrt'’.
A vector of transformed ChIP-seq counts.